Biotin and derivatives
Medchemexpress LLC LAIR1 Human Biotin 20ug
LAIR1 protein has a negative regulatory effect on NK cells B cells and T cells It activates the phosphatases PTPN6 and PTPN11 inhibits calcium increases in B cells and regulates cytokine production in CD4 T cells LAIR1 Protein Human (Biotinylated HEK293 Avi-His) is the recombinant human-derived LAIR1 protein expressed by HEK293 with C-Avi C-6 His labeled tag
Medchemexpress LLC DBCO-NHS ester 3 50mg | 1393350-27-0 | 416.43 g/mol | C24H20N2O5 | 50 MG
DBCO-NHS ester 3 is an amine-reactive dibenzylcyclooctyne (DBCO) N-hydroxysuccinimide (NHS) ester used for copper-free click chemistry and as a linker in antibody-drug conjugate and bioconjugation workflows. It reacts with primary amines to install a DBCO handle for strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-functionalized partners.
- Amine-reactive NHS ester for efficient conjugation to primary amines.
- Facilitates copper-free strain-promoted alkyne-azide cycloaddition (SPAAC).
- Suitable for use as a linker in antibody-drug conjugate and bioconjugation workflows.
- Supplied as a white to off-white solid, compatible with low-temperature storage.
- Typical purity around 95.6% and molecular weight 416.43 g/mol support reliable reaction performance.
Medchemexpress LLC Biotin-VAD-FMK | 1135688-15-1 | ≥98.0% | 672.81 g/mol | C30H49FN6O8S | 10 MG
Biotin-VAD-FMK is a cell-permeable, irreversible, biotin-labeled caspase inhibitor used to detect and label active caspases in cell lysates. The FMK electrophile covalently modifies active caspase catalytic residues, and the biotin tag enables downstream capture or detection with streptavidin-based reagents. Common uses include activity profiling and affinity capture in apoptosis research.
- Detects and labels active caspases in cell lysates.
- Covalent binding via FMK electrophile for durable labeling.
- Biotin tag enables streptavidin-based capture or detection.
- Cell-permeable for use in intact cells and lysates.
- Suitable for pull-downs, western blotting, and activity profiling.
- Stable powder with recommended frozen storage for long-term retention.
Medchemexpress LLC Tri-GalNAc biotin | 00-00-0 | 99.8% | C83H146N14O34S | 10MG
tri-GalNAc biotin is a biotinylated asialoglycoprotein receptor (ASGPR) ligand used for lysosome-targeting chimera (LYTAC) research. It promotes ASGPR-mediated cellular uptake of neutravidin and delivers bound protein to lysosomes for degradation. Supplied as a white to off-white solid, it is highly pure and suitable for in vitro and in vivo formulation studies.
- Biotinylated ASGPR ligand for lysosomal targeting studies.
- Promotes receptor-mediated uptake of neutravidin into cells.
- High purity suitable for research applications.
- Soluble in DMSO (100 mg/mL) for in vitro use.
- Formulatable in recommended in vivo vehicles at ≥2.5 mg/mL.
- Stable as a powder at -20°C for long-term storage.
Medchemexpress LLC Biotin-LC-LC-NHS | 89889-52-1 | 98.0% | 567.7 g/mol | C26H41N5O7S | 50 MG
Biotin-LC-LC-NHS is a long-chain N-hydroxysuccinimide (NHS) activated biotinylation reagent used to label proteins, antibodies, and small molecules. The LC-LC spacer reduces steric hindrance during conjugation, and the NHS ester reacts with primary amines to form stable amide bonds.
- Provides long-chain spacer (LC-LC) to reduce steric hindrance.
- Reactive NHS ester for amine-selective conjugation.
- Suitable for labeling antibodies and small molecules.
- Solid, white to light yellow appearance; store under inert gas and protect from light.
- Soluble in DMSO; follow recommended solvent and storage guidance.
Medchemexpress LLC Bis-SS-C3-NHS ester | 98604-88-7 | 98.0% | 432.47 g/mol | C16H20N2O8S2 | 100 MG
Bis-SS-C3-NHS ester is a cleavable antibody-drug conjugate (ADC) linker containing a disulfide-based spacer and N-hydroxysuccinimide (NHS) ester reactive groups for amine coupling. It is used to attach cytotoxic payloads to antibodies and enable controlled payload release inside target cells.
- Molecular formula: C16H20N2O8S2.
- Molecular weight: 432.47 g/mol.
- Cas number: 98604-88-7.
- Purity: 98.0%.
- Appearance: white to off-white solid.
- Storage: in solvent, -80°C for up to 6 months; -20°C for up to 1 month; store sealed and away from moisture.
- Available in multiple sizes, including 100 mg, for research use.
Medchemexpress LLC m-PEG6-NHS ester | 1449390-12-8 | >97.0% | 421.44 | C18H31NO10 | 250 MG
m-PEG6-NHS ester is a non-cleavable 6-unit polyethylene glycol (PEG) N-hydroxysuccinimide (NHS) ester used as a linker in antibody-drug conjugate (ADC) and proteolysis targeting chimera (PROTAC) synthesis, enabling efficient coupling to amine-containing ligands.
- Non-cleavable 6-unit PEG linker suitable for bioconjugation.
- High purity >97.0% to support research applications.
- Available in multiple pack sizes, including 250 MG.
- Molecular weight 421.44 g/mol and chemical formula C18H31NO10.
- Liquid, colorless to light yellow; store at -20°C (pure) or follow solvent storage recommendations.
- Includes datasheet and safety data sheet for handling and storage information.